Endocrine Abstracts

Background: Co secreting Thyrotropin/growth hormone pituitary adenomas are rare, and their clinical presentation and long term management may be challenging. Clinically, the majority of plurihormonal pituitary adenomas are silent and diagnosis almost always relies on immunohistochemical analysis of the tumor tissue. Early detection is key to optimize patient mamagement. We report a case of pituitary plurihormonal macroadenoma with overt clinical hyperthyroidism and minimal GH ...

IntroductionThe term collision tumor refers to the coexistence of two histologically distinct malignant neoplasms. The two malignancies can originate from the same organ or occur as metastases from other regions. This type of tumors involving the thyroid gland are especially rare. Reported cases are usually involving papillary thyroid carcinomas in coexistence with other types of tumors like medullary carcinoma, follicular carcinoma or metastasic disease...

IntroductionMalignant insulinoma is a rare pancreatic neuroendocrine tumor that accounts for only 10% of all cases of insulinoma. The clinical picture is characterized by the presence of severe hyperinsulinemic hypoglycaemic syndrome in a patient with pancreatic tumor with locoregional and/or distant metastases. Therapeutic management is challenging due to the need to control both hypoglycemic syndrome and tumor growth. Curative surgery is rarely applica...